Transcriptional silencing of Ets-1 oncogene contributes to human granulocytic differentiation
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چکیده
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منابع مشابه
Transcriptional silencing of the ETS1 oncogene contributes to human granulocytic differentiation.
BACKGROUND Ets-1 is a widely expressed transcription factor implicated in several biological processes including hematopoiesis, where it contributes to the regulation of cellular differentiation. The functions of Ets-1 are regulated by transcription factors as well as by phosphorylation events: phosphorylation of threonine 38 activates Ets-1, whereas phosphorylation of a cluster of serines with...
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